Fig. 7
From: Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells
Schematic of NK cell maturation, proliferation and survival in WT versus Stat5 DKI mice. WT mice (on the left) exhibit normal maturation, proliferation and survival of conventional NK cells and thymic NK cell cells. Stat5 DKI mice, which lack STAT5 tetramers (on the right), have defective NK cell maturation with decreased numbers of conventional NK cells as well as decreased numbers of thymic NK cells; their NK-cell proliferation is not defective, but Bcl2 expression is decreased and active caspases are increased, resulting in increased NK cell death
