Fig. 1

Crystal structure of the Ragulator complex. a Overall structure of the Ragulator complex in two different views. The Ragulator complex is shown as cylindrical cartoon model in a transparent envelope surface with p18 colored in pink, MP1 in green, p14 in blue, HBXIP in cyan, and C7orf59 in yellow, respectively. A schematic diagram of p18 is shown on the top with the interacting regions with MP1, C7orf59, HBXIP, and p14 are indicated. b Cylindrical cartoon presentations of the MP1-p14 and C7orf59-HBXIP heterodimers in the Ragulator complex. The secondary structure elements are labeled