Fig. 5 | Nature Communications

Fig. 5

From: Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae

Fig. 5The alt text for this image may have been generated using AI.

Impact of TacL deficiency on pneumococcal virulence. Survival of CD-1 mice after a intranasal infection with ~2.5 × 107 bioluminescent S. pneumoniae D39lux wild type, D39luxΔtacL, or the complemented mutant (D39ΔtacL pBAV-tacL) in the pneumonia model (n = 10) (see also Supplementary Fig. 14 for bioluminescence images). b Survival of CD-1 mice (n = 12) after intraperitoneal infection with ~3 × 103 pneumococci in the systemic infection model. **p < 0.01; ns not significant (Log-rank (Mantel–Cox) test)

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