Fig. 1 | Nature Communications

Fig. 1

From: The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile

Fig. 1

Reaction of the EtfAB/Bcd complex. In the first round the EtfAB/Bcd complex catalyzes the NADH-dependent reduction of β-FAD to β-FADH−, which bifurcates. One electron reduces α-FAD•− to α-FADH− and the other ferredoxin to ferredoxin−. α-FADH− swings to δ-FAD forming δ-FADH• and α-FAD•−, which returns to β-FAD. The second round generates a second ferredoxin− and δ-FADH−, which reduces crotonyl-CoA to butyryl-CoA

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