Fig. 2
From: Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition
Reproducible lncRNA regulation in independent validation data. a Correlation of mRNA expression fold-changes between TCGA and GSE9891. In each dataset, fold changes were measured in the mesenchymal (Mes) subtype compared to the epithelial (Epi) subtype. b Expression differences of lncRNA in mesenchymal subtype (n = 97) compared to epithelial subtype (n = 136) in GSE9891. ***P = 3.04 × 10−18; **P = 3.95 × 10−11; *P = 0.03; NS = no significant difference, one-tailed t-test; mean ± SEM. c Expression correlation of the lncRNA indicated with differentially expressed (DE) or non-differentially expressed (non-DE) genes in GSE9891. d Pathway enrichment analysis for the differentially expressed genes that were co-expressed with lncRNA. X- and Y-axes represent enrichment P-value of EMT-linked pathway for TCGA and GSE9891, respectively. Dashed lines denote P-value threshold of 0.05 (i.e., 1.301 in −log10 scale). P-values determined by BH adjusted hypergeometric test
