Table 1 Patients clinical details

From: Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Gender

Age

Diagnosis

Group of patients

First episode/relapse

Treatment

Urinary protein (g/mmol creatinine)

eGFR (ml/min/1.73 m 2 )

F

29

MCD

Control

Relapse

Corticosteroids

1.07

79

F

30

MCD

Control

Relapse

No treatment

0.19

73

M

66

MCD

Control

First episode

No treatment

0.56

55

F

31

MCD

Control

First episode

No treatment

NA

94

F

30

MN

Control

First episode

No treatment

0.08

89

M

46

MN

Control

First episode

No treatment

0.6

90

M

50

MN

Control

First episode

No treatment

>3

72

M

62

MPA

RPGN

First episode

No treatment

0.1

63

MPO-ANCA-positive

M

78

MPA

RPGN

First episode

Corticosteroids

0.23

39

PR3-ANCA-positive

M

52

MPA

RPGN

First episode

No treatment

0.41

47

MPO-ANCA-positive

F

46

MPA

RPGN

First episode

No treatment

0.26

18

MPO-ANCA-positive

M

47

MPA

RPGN

First episode

No treatment

0.27

6

MPO-ANCA-positive

F

58

MPA

RPGN

First episode

No treatment

Traces

6

MPO-ANCA-positive

M

44

MPA

RPGN

First episode

No treatment

0.08

55

MPO-ANCA-positive

M

68

GPA

RPGN

First episode

Corticosteroids

0.15

58

PR3-ANCA-positive

M

71

GPA

RPGN

First episode

No treatment

0.56

75

PR3-ANCA-positive

M

55

GPA

RPGN

Relapse

Corticosteroids

5

52

PR3-ANCA-positive

F

35

LN (class IV)

RPGN

Relapse

Corticosteroids

0.34

35

F

27

LN (class IV)

RPGN

Relapse

Corticosteroids

0.26

41

M

17

LN (class IV)

RPGN

First episode

No treatment

0.13

37

F

41

LN (class III)

RPGN

Relapse

Corticosteroids

0.19

25

F

25

LN (class III)

RPGN

First episode

No treatment

0.25

50

  1. Patients’ characteristics at the time of the kidney biopsy used in the study. The eGFR is calculated according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation
  2. MCD minimal change disease; MN membranous nephropathy; MPA microscopic polyangiitis; GPA granulomatosis with polyangiitis (GPA); ANCA anti-neutrophil cytoplasmic antibodies; MPO myeloperoxidase; PR3 proteinase 3; LN class III and class IV lupus nephritis, control for non-crescentic glomerular disease and RPGN for crescentic RPGN