Fig. 4 | Nature Communications

Fig. 4

From: Genome-wide identification and differential analysis of translational initiation

Fig. 4

Genome-wide identification and differential analysis of TIs. a rRibo-seq and LTM-based TI-seq RPF count profiles in HEK293 cell line for TUBA1B, suggesting a uORF being translated across a different reading frame (pink) from annotated one (skyblue). b The normalized QTI-seq RPF count profiles under normal condition and amino-acid deprivation for the longest isoform of C1QBP. The top enriched c biological processes and d cellular components, based on the GO enrichment analysis of the genes with significantly elevated translation initiation efficiency under amino-acid deprivation. The normalized QTI-seq RPF and RNA-seq count profiles under normal condition and amino-acid deprivation for genes encoding mitochondrial ribosomal proteins e MRPL27 and f MRPS14

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