Fig. 6
From: Designable and dynamic single-walled stiff nanotubes assembled from sequence-defined peptoids
Designability and applications of PNTs. a Structures of seven functionalized APOs. b AFM height image of one PNT assembled from CD-APO2 (scale bar, 150 nm); the insert is the height measurement showing the PNT height of about 12.2 nm. c TEM image of one PNT assembled from CD-APO2 (scale bar, 20 nm). d AFM height image of PNTs assembled from RGDG-APO2 (scale bar, 200 nm). e X-ray diffraction (XRD) data of PNTs assembled from APO2 (magenta), CE-APO2 (blue), DOP-APO2 (black), SSYA-APO2 (green), CD-APO2 (orange), or RGDG-APO2 (cyan); all of these PNTs show similar XRD peaks, indicating they all have similar structures. f UV/Vis spectra showing the removal of 4-aminoazbenzene (azo) from water. Red line represents azo-contaminated water; black line represents the CD-APO2-PNT decontaminated water. g–i Optical images (scale bar, 50 μm) of A549 cancer cells absorbed on the RGDG-APO2-PNT-treated glass slide (g), APO2-PNT-treated glass slide (h), and on the bare glass slide (i). j The chart shows that the cell density of RGDG-APO2-PNT-treated glass slide is dramatically higher than those of control slides. k, l Fluorescent images showing the cellular uptake of sonication-cut-PNTs (in red color) co-assembled from APO2, RGDG-APO2, and Rb-APO2 with a molar ratio of 8:1:1 (scale bar, 8.0 μm) (k) and from APO2 and Rb-APO2 with a molar ratio of 9:1 (scale bar, 5.0 μm) (l), followed by staining with cytoskeleton actin (green) and DAPI (blue); the significantly higher density of red spots observed in Fig. 6k indicates that RGD-containing PNTs exhibited an enhanced cellular adhesion and uptake within A549 live cells
