Fig. 2
Effects of mcr-1 overexpression on bacterial growth and fitness in vitro. a Overproducing mcr-1 causes variable effects on growth rate depending on the concentrations of l-arabinose (n = 3). b The expression levels of mcr-1 gene induced by increasing concentrations of arabinose were measured by qRT-PCR (n = 2). c Relative fitness of mcr-1 overexpressing strain mcr-1/pBAD competing control strain pHT315 under increasing concentrations of l-arabinose (0.0002% vs 0%, 0.002% vs 0%, 0.02% vs 0%, 0.2% vs 0%). Error bars represent the SD (n = 6). The differences in fitness were tested using non-parametric Mann–Whitney test, ** indicates the p values is <0.05. The average relative fitness and p values are listed in Supplementary Table 6
