Table 4 Trans-acting SNP association results for three proteins with significant pQTL signal during LCD

From: Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Protein

SNP

Chr

Position

MA

MAF

Coef

SE

p value

Adjusted p value

Angiotensinogen

rs13200531

6

23242826

G

0.07

-0.22

0.036

3.88 × 10−10

1.19 × 10−10

Leptin

rs9344031

6

81400749

G

0.10

0.31

0.059

1.48 × 10−7

1.11 × 10−7

Leptin

rs481777

6

81578293

G

0.24

0.22

0.042

1.38 × 10−7

5.57 × 10−6

Caspase-10

rs1544241

18

855264

T

0.44

0.09

0.017

1.57 × 10−7

2.36 × 10−7

  1. MAF, pQTL p value (pvalue) and corresponding tested protein are provided
  2. SNP single-nucleotide polymorphism, Chr chromosome, MA minor allele, MAF minor allele frequency, Coef estimated association coefficient, SE standard error
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