Fig. 1
From: Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
Strategy for combining the pharmacophores of clinically used HDAC inhibitors and a preclinical LSD1 inhibitor to generate dual action HDAC-LSD1 inhibitors. Blue—incorporated LSD1 inhibitor features, Green—incorporated HDAC inhibitor features, Orange—shared structural features, Black—features not incorporated into dual inhibitors
