Fig. 3
From: Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution
BaseScope detection of CRC subclonal architecture. a Representative images showing BaseScope detection of a small patch of mutant cells (red) within a field of wild-type cells (yellow). Scale bars represent 200 micron. b Representative topographical maps of subclonal architecture showing the spatial arrangement of mutant (red) and wild-type (yellow) subclones. Examples of low mixing (left column), intermediate mixing (middle column) and high mixing (right column) are shown. Scale bars represent 2000 micron
