Fig. 8
From: Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA

Cooperative binding of NUFIP2 and Roquin to response elements in ICOS and Ox40 mRNA. a EMSA performed with the ICOS (nt 2183–2271) RNA (a–c) or Ox40 (nt 1064–1126) RNA (d–f) using increasing amounts (0–4860 nm) of NUFIP2 (aa 255–411) (a, d) or increasing amounts (0–200 nm) of Roquin-1 (aa 2–441) (b, e), or using increasing amounts (0–200 nm) of Roquin-1 (aa 2–441) in the presence or absence of 540 nm NUFIP2 (c, f)