Fig. 2 | Nature Communications

Fig. 2

From: Long-acting injectable atovaquone nanomedicines for malaria prophylaxis

Fig. 2The alternative text for this image may have been generated using AI.

Creation and screening of atovaquone nanoformulations. a Hydrophobic hydroxynaphthoquinone atovaquone was formulated to generate candidate ATQSDN nanoparticles. b ATQSDN library was screened for Z-average nanoparticle diameter after dispersion into water (0.5 mg mL−1, 25 °C); 'hits' (solid bars) were selected for further evaluation. c Eleven ATQSDN 'hits' were evaluated using an in vitro rapid equilibrium dialysis intramuscular depot model assay (SIF) using ATQSDN formulation prepared with 3H-labelled atovaquone

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