Fig. 5 | Nature Communications

Fig. 5

From: Engineering human pluripotent stem cells into a functional skeletal muscle tissue

Fig. 5

mRNA expression during 2D and 3D differentiation of hPSC-derived iMPCs. a Heat-map of mRNA expression in monolayers (2D) and iSKM bundles (3D) at 1, 2, and 4 weeks of differentiation, shown for three independent experiments. b, c qPCR results for different myosin heavy chain (MYH) isoforms (b) and calcium handling related genes (c). (*P < 0.05 vs. 1wk, #P < 0.05 vs. 2D group, Tukey–Kramer HSD test; n = 6–8 monolayers or bundles from three differentiations, data are presented as mean ± SEM)

Back to article page