Table 3 Heritability enrichment of ten grouped cell types
Category | Proportion of SNPs (%) | Proportion of \({\boldsymbol h}_{\boldsymbol g}^{\boldsymbol 2}\) (%) | Enrichment (standard errors) | P-value |
|---|---|---|---|---|
Kidney | 4.26 | 27.27 | 6.4 (2.44) | 0.027 |
Liver | 7.22 | 37.68 | 5.22 (1.55) | 0.01 |
Gastrointestinal | 16.77 | 72.88 | 4.35 (0.97) | 0.0017 |
Immune and hematopoietic | 23.34 | 100.17 | 4.29 (0.76) | 2.20E-05 |
Central nervous system | 14.88 | 54.09 | 3.64 (0.87) | 0.0039 |
Cardiovascular | 11.11 | 35.74 | 3.22 (1.26) | 0.078 |
Connective tissue/bone | 11.5 | 35.65 | 3.1 (1.04) | 0.037 |
Adrenal/pancreas | 9.36 | 26.17 | 2.8 (1.31) | 0.18 |
Other | 20.27 | 56.68 | 2.8 (0.98) | 0.076 |
Skeletal Muscle | 10.38 | 14.29 | 1.38 (1.25) | 0.76 |
