Table 1 Runtimes of the compared methods

From: High-throughput immune repertoire analysis with IGoR

Chain

(Pre)alignments

Probabilistic treatment

 

MiXCR

Partis

IGoR/RepgenHMM

MiXCR

Partis

RepgenHMM

IGoR

TRA 100 bp

2 × 10−4

NA

0.3

NA

NA

10−2

10−4

TRB 60 bp

3 × 10−4

NA

0.1

NA

NA

1

0.1

IGH 130 bp

10−3

10−2

0.2

NA

5 × 10−2

>1

0.2

  1. Times for alignments are in seconds per sequence. In the probabilistic treatment, times are in seconds per sequence per iteration for Partis, and in seconds per sequence per EM iteration for IGoR and repgenHMM. MiXCR only performs alignments and does not include a probabilistic treatment. Partis only handles BCRs. IGoR and repgenHMM share the same code for pre-alignment. NA not applicable