Fig. 3

Biophysical characterization of NR1. a 2.6 Å X-ray crystal structure of C-terminal truncated Rheb bound to NR1. Side-chains of residues within 4 Å of NR1 are shown in stick representation. b Ligand interaction diagram of NR1 bound to Rheb; side-chains of residues within 4 Å of the ligand are shown. c Another view of the X-ray structure of NR1 bound to Rheb; side-chains of residues implicated in activating mTORC1 are shown. d Stereo image of NR1 bound to Rheb