Fig. 3 | Nature Communications

Fig. 3

From: Non-equivalent antigen presenting capabilities of dendritic cells and macrophages in generating brain-infiltrating CD8+ T cell responses

Fig. 3

Splenic TCR repertoire is not markedly affected by cell-specific H-2Kb deletion. Splenocytes were isolated from naïve 6–8-week-old animals (N = 3 per group) and stained with anti-CD45, anti-CD4, and anti-CD8 antibodies, as well as antibodies specific to each of the T-cell receptor Vβ regions listed. CD8+ T cells (a) and CD4+ T cells (b) isolated from the spleen show highly similar T-cell repertoires, with TCR Vβ5 only impacted peripherally. Data presented as mean with error bars representing standard error of the mean (SEM). * denotes p < 0.05 as measured by two-way ANOVA with Holm−Sidak correction

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