Table 4 APRT allele spectrum of excised populations following FACS enrichment
From: Microhomology-assisted scarless genome editing in human iPSCs
Non-targeted | NHEJ | MMEJ | |||||
|---|---|---|---|---|---|---|---|
mCh Pop. | Samples analyzed | Normal allele | Indel | NHEJ (perfect) | Silent ONLY | APRT*J & Silent | Fidelity (%) |
low | 56 | 1 | 21 | 25 (10) | 2 | 7 | 16.1 |
high | 49 | 2 | 3 | 34 (21) | 1 | 9 | 20.4 |
