Fig. 1
From: Structure-based design of chimeric antigens for multivalent protein vaccines

Structure-based design of ChAs. a Schematic of meningococcal cell surface, depicting the key surface-exposed antigens, fHbp and PorA. b Location of fHbp residues replaced with VR2 P1.16. c Analysis of recombinant ChAs by SDS-PAGE and western blot. Immunoblots are probed with α-V1.1 fHbp pAb and α-PorA P1.16 mAb. Complete gel and western blots are shown in Supplementary Figure 5