Fig. 2 | Nature Communications

Fig. 2

From: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

Fig. 2

Regional plots of association results and recombination rates for the identified risk loci. a 8q24.21 (rs28665337), b 2q22.3 (rs17481869). Plots (generated using visPIG14) show association −log10P-values (left y-axis) of genotyped (triangles) and imputed (circles) SNPs in the GWAS samples (2442 cases and 14,609 controls) and recombination rates (right y-axis). −log10P-values were calculated assuming an additive model in SNPTEST v2.5.2 and are shown according to their chromosomal positions (x-axis). Lead SNPs are denoted by large circles or triangles labeled by rsID. Color intensity of each symbol reflects LD, white (r2 = 0), dark red (r2 = 1.0). Light blue line shows recombination rates from UK10K Genomes Project. Genome coordinates are from NCBI human genome GRCh37

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