Fig. 2
From: A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
The N-terminal mRNA-binding region of Syncrip folds as a two-domain structural unit centred on a novel αββ element. a Cartoon representation of the structure of the NeR1 construct (aa 18–243). The N-terminal domain is coloured in green, the αββ extension in yellow and the canonical RRM1 in blue. The dashed grey line indicates the flexible linker between the two domains, which is not visible in the electron density map. b Surface representation of the di-domain. The RRM1 extension bridges the gap between the N-terminal and core RRM folds
