Fig. 5
From: A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
The N-terminal domain of Syncrip is a novel sequence-specific N-terminal unit for RNA recognition (NURR). a Residues conserved (identical) in human and Drosophila are coloured in red on the structures of human (PDB ID: 2MXT) and Drosophila Syncrip (this study) N-terminal domains. The smaller images show 180° rotations of the structures. b Chemical shift changes upon binding the randomised 4N RNA are mapped in blue on the surface of the NURR domains. The smaller images show 180° rotations of the structures. c SIA scores for the human and Drosophila NURR domain, reflecting the nucleobase preferences at the different positions of the bound sequence. In this representation, the relative height of the four columns in each position represent the relative preference of the domain for the four nucleobases
