Table 1 Syncrip constructs used in this study
From: A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
Abbreviations | Construct description | Construct boundaries |
|---|---|---|
N | Syncrip N-terminal domain | Dm: residues 16–109 |
Hs: residues 16–109 | ||
eR1 | Syncrip extended RRM1 | Dm: residues 118–243 |
Hs: residues 118–242 | ||
NeR1 | Syncrip N-terminal and extended RRM1 domains | Dm: residues 16–243 |
Hs: residues 16–242 | ||
NeR1 R60A G97L | Syncrip N-terminal and extended RRM1 domains contacting two mutated residues | Hs: residues 16–242 |
eR1R2R3 | Syncrip extended RRM1, RRM2 and RRM3 domains. | Hs: residues 118–428 |
NeR1R2R3 | Syncrip N-terminal, extended RRM1, RRM2 and RRM3 domains. | Hs: residues 16–428 |
