Fig. 6
From: Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells
Treatment response in Patient 3. This 76-year-old patient had a bilateral GBM tumor and was treated with radiation and concomitant temozolomide, with tumor progression four months into the temozolomide regimen. The patient received a total of eight injections of autologous cytotoxic lymphocytes, and stable disease was achieved within one month after the first injection. The MR images (top panel) illustrate a continuous reduction in size of the contrast-enhancing lesion by 63% over a course of 542 days. The middle and lower panels represent FET-PET images at two different levels of the brain, showing a 50% reduction in metabolically active tumor volume over the course of one year. The green areas represent the invasive parts of the tumor
