Fig. 4

Diverse usage of TCRα–TCRβ pairings within CD38⁺HLA-DR⁺CD8⁺ T cells. The frequency of TCRαβ clonotypes within particular TRAV–TRBV paired segments is shown for individual patients: a non-HLA-A*02:01 surviving individuals; b HLA-A*02:01 surviving individuals; c patients with a fatal disease outcome. Pulled data from all the time-points is shown, as summarized in Supplementary Table 5. d The number of specific TRBV–TRAV paired segments utilized per donor is shown for non-HLA-A*02:01 surviving patients, HLA-A*02:01 surviving patients and fatal patients for CD38⁺HLA-DR⁺CD8⁺ T cells as well for H7N9 surviving patient and healthy individuals for A2-M1₅₈⁺CD8⁺ T cells