Fig. 2 | Nature Communications

Fig. 2

From: Dissecting super-enhancer hierarchy based on chromatin interactions

Fig. 2

Chromatin landscapes at hub enhancers in K562 cells. a–f Spatial distribution of chromatin marks centered by enhancers in four groups, hub (n = 444), non-hub (n = 2303) enhancers, enhancers in non-hierarchical SEs (n = 4290) and regular enhancers (n = 22477): H3K4me1 (a), H3K27ac (b), DNase I hypersensitivity (c), master regulators GATA1 (d) and TAL1 (e), coactivator p300 (f). P values were calculated using Student’s t-test based on the ChIP-seq signal intensity within 1 kb window centered by enhancers. *P < 0.05; **P < 0.01; ***P < 0.001, n.s. not significant

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