Fig. 4
From: Asymmetric synthesis of γ-branched amines via rhodium-catalyzed reductive amination
Scope of allylamine. a: General reaction conditions: allylic diethylamine 4 (0.24 mmol, 1.0 equiv, E/Z > 99:1 unless otherwise noted), nucleophile 2 (1.2 equiv), HCO2H (3.0 equiv), THF (1.2 M). b: Substrate E/Z = 96.7:3.3. c: Substrate Z/E > 99:1. d: 1,4-dioxane used. e: Substrate Z/E = 95.6:4.4. f: Toluene used. See supplementary methods for details. The absolute configuration of product is determined by alkene configuration
