Fig. 6
From: Asymmetric synthesis of γ-branched amines via rhodium-catalyzed reductive amination
Control experiments and proposed catalytic cycles. a Selectivity of the enamine exchange step. b Thermodynamic equilibrium for the enamine exchange. c Selectivity of the transfer hydrogenation step (simultaneous addition of amine and hydrogen donor). d Chemoselectivity for various secondary amine nucleophiles under standard conditions. e Proposed catalytic cycles: enantioselective isomerization and transfer hydrogenation, X = BAr4F
