Fig. 6
Similarity between belimumab HCDR3 and the DxL(V/L) motif. a Comparison of BAFF binding among BR3, BCMA, and the belimumab HCDR loops at the BAFF surface (black and gray for each protomer). b The conformations of the DxL(V/L) motifs within BR3 (green), BCMA (yellow), and the belimumab HCDR3 loop (blue). The key residues in the DxL(V/L) motifs are labeled. In a and b, the DxL(V/L) motifs are indicated by blue circles. c Amino acid sequence comparison between the belimumab HCDR3 loop and the DxL(V/L) motifs of BAFF receptors. Conserved residues are colored red
