Fig. 1 | Nature Communications

Fig. 1

From: Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs

Fig. 1The alternative text for this image may have been generated using AI.

Cell-type-specific genes inhibit reprogramming. a Outline of the screening strategy used to identify factors that inhibit reprogramming. b Cell-type-specific genes are enriched by the screenings. Genes enriched in the second screening of NPCs and the high positive fraction in the screening of hepatoblasts were subjected to tissue expression analysis with DAVID18, 19. Fisher’s exact test. c Factors that inhibit reprogramming are different among cell types. Identified genes from the second screening of NPCs, the high positive fraction in the screening of hepatoblasts and Yang et al.20 were used to generate the Venn diagram. Numbers indicate the number of genes

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