Fig. 1 | Nature Communications

Fig. 1

From: Integrated genetic and epigenetic analysis of myxofibrosarcoma

Fig. 1

Driver gene landscape in 116 MFSs. Driver genes are ranked according to their frequencies of mutations. In each pathway, mutually exclusive profile was found: RB1, CDKN2A/CDKN2B, and CCND1 in p53 signaling and the cell cycle G1/S checkpoint pathways; NF1, NTRK1, KRAS, PTEN, SYK, PIK3CA, and BRAF in the RTK-RAS-PI3K pathway; and ATRX, TET2, SETD2, WT1, and HIST1H3B in regulators of the epigenome

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