Fig. 3

CP1 increases TILs and tumor immune infiltration while decreasing Tregs. a Blinded IHC with representative images (scale bar, 100 μm) and b–m flow cytometry analysis of Myc-CaP tumors or dLNs, as indicated, displayed as cell counts normalized to tumor volume (scatter plots) or percentages of parent gate (scatter boxed plots), with representative flow cytometry plots. MDSCs were defined as CD11b⁺Gr-1⁺. n Multiplex cytokine and chemokine array from Myc-CaP tumors. Mice n = 4–5/group, performed in two independent experiments. Data represented as mean ± S.E.M. or log₂ fold change with and without CP1 administration. Statistical significance was determined by two-tailed Student’s t-test. *P < 0.05, **P < 0.01, ***P < 0.001