Table 2 Deep-layer enriched astrocytic genes

From: Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

Gene symbol

RPKM

Fold change (deep/upper)

  
 

Upper

Deep

 

P value

Known functions in astrocytes (Refs)

Id1

3.7

43.9

11.6

0.035

 

Cxcr7

0.7

5.6

8.9

0.0017

Regulation of proliferation ([43])

Id3

126.2

529.8

4.2

0.0030

 

Fgfbp3

3.6

9.0

2.9

0.017

 

Sparc

20.4

40.9

2.0

0.013

Negative regulation of synapse formation ([41,44])

Gfap

11.7

23.5

2.0

0.045

Regulation of neuron-astrocyte communication ([42])

  1. Average RPKM and fold changes are shown (n = 3 brains). P value, paired t-test
  2. See Supplementary Data 2 and 3 for full gene lists of deep-layer enriched genes
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