Fig. 3 | Nature Communications

Fig. 3

From: Knowledge acquisition is governed by striatal prediction errors

Fig. 3

Brain regions correlating with PE magnitude and valence during feedback. a Substantial clusters of activity were observed bilaterally in ventral and dorsal striatum, DLPFC, cingulate cortex, inferior parietal cortex, and precuneus (Supplementary TableĀ 1). Within the striatum, one cluster was centered on the NAc and another in posterior areas of the putamen/claustrum, extending through to insula and (on the right) anterior MTL. b Activity in these regions parametrically varied with the signed PE on each trial, such that the greatest responses were elicited by better-than-expected outcomes (feedback for correctly answered questions stated with low confidence—large positive PE events), and the smallest responses by worse-than-expected events (feedback for incorrect answers stated with high confidence—large negative PE). Importantly, responses to fully predicted outcomes (zero PE feedback, whether for correct or incorrect answers) lay in the middle. The plots depict average single-trial beta estimates for each PE value, within selected ROIs

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