Fig. 5 | Nature Communications

Fig. 5

From: Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

Fig. 5

Acute oxidative stress inhibits GAPDH activity to amplify NADPH production in the PPP. a Relative ratios of indicated intracellular glycolytic metabolites after treatment with 500 µM hydrogen peroxide for 15 min. b Isotopologue distribution of intracellular metabolites in glycolysis and the pentose phosphate pathway after incubation with 13C6-glucose and 500 µM hydrogen peroxide for 15 min. a, b All graphs show mean (S.D.) of three independent experiments with triplicate measurements

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