Fig. 5 | Nature Communications

Fig. 5

From: The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma

Fig. 5

PRMT5 mediates LINC01138-driven HCC cell growth, migration and invasion. a Rescue assays of colony formation assay were performed after silencing PRMT5 in pWPXL-LINC01138 cells. b Rescue assays of transwell invasion assay were performed after silencing PRMT5 in pWPXL-LINC01138 cells. c GSEA enrichment focused on a set of signalling pathways and biological processes after LINC01138 silencing and PRMT5 silencing, summarized based on the enrichment score (signalling pathway, blue; biological process, green). d Correlation analysis of the gene expression profiling between the si-LINC01138 group and si-PRMT5 group. e The mRNA levels of tumorigenesis-related genes in the high-scored four signalling pathways in cells with indicated treatments. Values are expressed as the mean ± SEM, n = 3 in a, b, d, e. **P < 0.01 and ***P < 0.001

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