Fig. 1 | Nature Communications

Fig. 1

From: Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure

Fig. 1

Manhattan plot of ease of skin tanning results in the UKBB data set. The P values were obtained by logistic regression analysis assuming an additive genetic model with sex and the first five principal components of the genotype data as covariates. The x-axis shows the genomic coordinates (GRCh37.p13) of the tested SNPs and the y-axis shows the –log10 P value of their association. The horizontal red line indicates the threshold for genome-wide significance at 5.0 × 10−8. The ten genes that failed replication are indicated by *; genes newly associated with tanning ability are reported in orange

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