Fig. 5
From: Manipulation of insulin signaling phenocopies evolution of a host-associated polyphenism
Manipulation of insulin signaling alters wing morph reaction norms. Effects of RNAi treatment on the frequency of short-wing morphs in Cardiospermum (top row) and Koelreuteria (bottom row) ecotypes. Unmanipulated bugs (left column) differ in their reaction norms based on ecotype. In the Cardiospermum ecotype, RNAi targeting FoxO or injection of exogenous insulin significantly alter the reaction norm, making it resemble the Koelreuteria ecotype. Knockdown of both insulin receptor genes in the Koelreuteria ecotype produces a marginal decrease in the rate of short-winged adults. Each point represents a treatment cohort of multiple individuals. Point size indicates relative survival rate. These data include 4218 scored adults (820 from RNAi) in 187 cohorts (59 RNAi treatments)
