Fig. 5
From: Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs
A subset of promoters display a primed accessibility structure. a For all genes with significant gene expression changes between Div8+ and Div0, the change in gene expression is plotted vs. their promoter accessibility at Div0. Genes in which both expression and accessibility (log2 rppm < 3) was induced are labeled in red, and genes in which expression is increased at Div8+ but were highly accessibility at Div0 (log2 rppm > 5) were labeled as primed (gold). b For induced and primed gene sets, the promoter accessibility and gene expression kinetics are shown across all divisions. Boxplot center line indicates data median, lower and upper bounds of boxes the 1st and 3rd quartile ranges, and whiskers the upper and lower ranges of the data. Significance between Div0 and Div8+ was determined by two-tailed Student’s T-test. c The promoter accessibility and gene expression changes across all divisions for the indicated gene promoters with a primed (top) or induced (bottom) accessibility pattern. d Gene ontology results for primed accessible loci in gold from a
