Fig. 7
From: Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation
Model of Hox gene function in early development of an anthozoan. a Illustration depicting anterior Hox (NvAx6) (red) and central/posterior Hox (NvAx1) (blue/green) expression throughout early development of N. vectensis. b Working model of how anterior (NvAx6) and central/posterior (NvAx1) Hox genes function to specify the oral–aboral axis before and during gastrulation in an anthozoan cnidarian. c Illustration of known regulatory relationships between Hox genes and the oral (NvWntA, NvWnt1, NvWnt2, NvWnt3, NvWnt4, NvFoxA, NvBrachyury, and NvSnailA) and aboral (NvSix3/6, NvFgf2A, NvSfrp1/5, and NvDkk1/2/4) markers assessed in this study. Important components of this regulatory paradigm needing description are marked with roman numerals (I–IX) with corresponding text at the periphery of the illustration. Regulatory relationships derived from previous studies are cited in the periphery text (I, II, VI, and VIII)
