Table 1 Evaluation of chiral ligands
From: Silicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation
| ||||||
|---|---|---|---|---|---|---|
Entry | Ligand | Conv. (%) | Yield (%) | 2a/3a | ee (%) | |
2a+3a | 4a | |||||
1 | L1 | 98 | 96 | 2 | >99 | 92 |
2 | L2 | >99 | >99 | 0 | >99 | 42 |
3 | L3 | 99 | 99 | 0 | >99 | 48 |
4 | L4 | >99 | >99 | 0 | >99 | 80 |
5 | L5 | 94 | 94 | 0 | >99 | 60 |
6 | L6 | 44 | 29 | 15 | >99 | −9 |
