Fig. 3

Actin–actin interactions. The P-end is at the top. a Comparison of the intrastrand interactions between F-actin (5JLF, yellow and cyan) and cofilactin (green and camel). The structures are aligned through superimposition of the IDs. The residues that are found in the interface of both F-actin and cofilactin are colored blue, while those found solely in F-actin are colored red. b A 90° rotation of a. c An enlargement of the intrastrand interactions in cofilactin in the rectangle in b. The side chains on the interface are shown as a ball and stick model. Arg62, the only residue of the outer domain contributing to the intrastrand interactions, is presented in yellow. d Interstrand interactions of F-actin. The interface residues, whose side chains form the interface, are shown as a space-filling model. The interface residues of the yellow subunit are shown in orange, and the other residues are shown in blue. e Interstrand interactions of cofilactin. The interface residues in a space-filling model of the green subunit are shown in orange and the other residues are shown in blue