Fig. 3

Integrative analysis identified 13 clusters with significantly enriched DMERs. a The 13 enriched clusters are shown with the number of DMERs in each cluster. Below, the relative abundance of various types of differential marks is shown and demonstrates the high abundance of active enhancer and active promoter marks (section I and II). Nine clusters are associated with active enhancers and four with active promoters. b Characterization of three clusters with the most DMERs (1, 7, and 8). Top DMGs (left) and top enriched biological pathways associated with these genes (right) are shown