Table 1 Clinical characteristics associated with blood MAIT cell frequency using linear regression

Variable	Regression coefficient	95% CI		p
Variable	Regression coefficient	Lower bound	Higher bound	p
a. Univariate analysis
Among the entire population
Age	−0.034	−0.057	−0.011	<0.01
Male sex	−0.538	−1.16	0.084	0.09
Cirrhosis	−1.918	−2.426	−1.41	<0.01
Among patients with cirrhosis
Alcohol-related cirrhosis	−0.187	−0.63	0.256	0.40
NASH-related cirrhosis	−0.04	−0.502	0.421	0.86
Child–Pugh score	0.004	−0.057	0.064	0.90
MELD score	0.001	−0.021	0.024	0.89
Ascites	0.019	−0.331	0.369	0.91
Encephalopathy	0.188	−0.217	0.594	0.36
Chronic antibiotic prophylaxis (norfloxacin and/or rifaximin) (%)	0.582	0.093	1.072	0.02
Beta-blockers	−0.016	−0.08	0.049	0.63
b. Bivariate analysis
Among the entire population
Age	−0.034	−0.057	−0.011	<0.01
Cirrhosis	−1.52	−2.206	−0.834	<0.01
Among patients with cirrhosis
Age	0.012	−0.003	0.028	0.11
Chronic antibiotic prophylaxis (norfloxacin and/or rifaximin)	0.55	0.067	1.033	0.03

a. The potential relationship between patient characteristics and blood MAIT cell frequency was analyzed by linear regression univariate analysis
b. Each variable achieving a p-value < 0.05 was then introduced into a bivariate model, including the age to determine whether these variables predicted blood MAIT cell frequency independently of age

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