Table 1 Characteristics of the POAG cases and controls from GERA cohort

From: A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci

  

Controls

Cases

Total

N (proportion that are cases)

58 426

4 986 (7.9%)

Age (years)

Mean ± SD

69.7 ± 13.0

79.6 ± 9.4

Sex

Women - N (proportion that are cases)

35 193

2 689 (7.1%)

 

Men - N (proportion that are cases)

23 233

2 297 (9.0%)

NTG cases

N

743

Controls with an OHTN diagnosis

N

881

Median IOP

Mean ± SD

14.9 ± 2.6

15.5 ± 2.9

Non-Hispanic white

N (proportion that are cases)

48 065

3 836 (7.4%)

 

Age (years), mean ± SD

70.7 ± 12.5

80.5 ± 9.0

 

Sex, number of women/men

28 798/19 266

2 115/1 721

Hispanic/Latino

N (proportion that are cases)

4 778

411 (7.9%)

 

Age (years) Mean ± SD

65.0 ± 14.4

75.5 ± 10.1

 

Sex, number of Women / Men

2 965/1 813

218/193

East Asian

N (proportion that are cases)

4 034

441 (9.9%)

 

Age (years), mean ± SD

64.6 ± 14.4

76.6 ± 10.0

 

Sex, number of women/men

2 453/1 581

202/239

African-American

N (proportion that are cases)

1 549

298 (16.1%)

 

Age (years), mean ± SD

66.7 ± 13.3

77.7 ± 9.3

 

Sex, number of women/men

976/573

154/144

  1. N number, SD standard deviation, POAG primary open-angle glaucoma, NTG normal tension glaucoma, OHTN ocular hypertension, defined as participants who had a diagnosis of ocular hypertension but have no diagnosis of any type of glaucoma, IOP intraocular pressure, Age age at last vision exam