Fig. 1 | Nature Communications

Fig. 1

From: Resolving molecule-specific information in dynamic lipid membrane processes with multi-resonant infrared metasurfaces

Fig. 1

Nanophotonic label-free biosensor for chemically distinguishing multiple analytes in biological samples. a Multi-resonant mid-IR nanoantennas are leveraged to enhance the vibrational–absorption signals associated with biomimetic lipid membrane formation, polypeptide/membrane interaction, and vesicular cargo release on the sensor surface. b Antenna resonance positions are engineered to simultaneously overlap with the vibrational signatures of both the amide I, II, and the CH2, CH3 absorption bands, allowing for the simultaneous enhancement and detection of lipid- and protein-induced absorption changes. The 3D model of melittin used in this figure was imported from RSCB Protein Data Bank, DOI: 10.2210/pdb2MLT/pdb, which was deposited by D. Eisenberg, M. Gribskov, and T.C. Terwilliger. All rights reserved

Back to article page