Fig. 6 | Nature Communications

Fig. 6

From: A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

Fig. 6The alternative text for this image may have been generated using AI.

Characterisation of ERα interactors from in vivo samples. a Schematic representation of the ERα qPLEX-RIME workflow in human xenograft tissues or in human breast cancer tumours. b Volcano plot summarising the quantitative results of the ERα interactome in human breast cancer tumours. Several well-known ERα interactors are labelled. c Boxplots illustrating the enrichment of selected known ERα interactors in the ERα samples compared to IgG controls in human breast cancer tissues. The log2 values are normalised so that the median of IgGs is zero. Centre line shows the median, bounds of box correspond to the first and third quartiles and the upper and lower whiskers extend to the largest or the smallest value no further than 1.5 × IQR (inter-quartile range)

Back to article page