Table 1 SL partners and corresponding drug combinations tested in patient-derived melanoma cell lines

From: Harnessing synthetic lethality to predict the response to cancer treatment

View full size image

  1. The table shows the top two predicted cSL interactions tested in melanoma, the corresponding drugs tested and the experiments’ outcome as evaluated by the combination index (CI) at 50% of cells are affected (CI < 0.7: strong synergism (blue), CI < 1: moderate synergism (green), and CI > 1: no synergism (white)).